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Patients experience a wide range of symptoms beyond severe pain and tophi, including1,2

  • Acute and persistent inflammatory arthritis2
  • Disability associated with bone and joint destruction3
  • Potential to lead to osteoarthritis2
  • Mineral and bone disorder in CKD4
  • Ischemic heart disease and CHF5-7

See how uncontrolled gout affects patients’ daily lives

CHF, chronic heart failure; CKD, chronic kidney disease.


  1. Nickeleit V, et al. Nephrol Dial Transplant. 1997;12(9):1832-1838.
  2. Klauser AS, et al. JAMA Cardiol. 2019;4(10):1019-1028.
  3. Doghramji PP, et al. Postgrad Med. 2012;124(6):98-109.
  4. Dalbeth N, et al. Lancet. 2016;388(10055):2039-2052.
  5. Park JJ, et al. BMJ Open. 2014;4(7):e005308.
  6. Khanna PP, et al. J Clin Med. 2020;9(10):3204.
  7. Becker MA, et al. Ann Rheum Dis. 2013;72(9):1469-1474.